Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968243 | 0.99 | ACHE (0.59) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968960 | 0.89 | ACHE (0.57) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969889 | 0.88 | ACHE (0.62) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969228 | 0.88 | ACHE (0.48) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969798 | 0.87 | ACHE (0.59) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968562 | 0.87 | ACHE (0.65) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8970150 | 0.87 | ACHE (0.50) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968605 | 0.83 | ACHE (0.56) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968853 | 0.81 | ACHE (0.51) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969376 | 0.81 | ACHE (0.51) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |