Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969535 | 0.97 | RARB (0.39) | RARBENPP2S1PR1HTTMAPT | |
| SCHEMBL8969505 | 0.91 | RARB (0.37) | RARBENPP2S1PR1S1PR3SPHK2 | |
| SCHEMBL8969305 | 0.89 | RARB (0.41) | RARBENPP2S1PR1HTTMAPT | |
| SCHEMBL8969780 | 0.87 | CNR2 (0.34) | RARBENPP2 | |
| SCHEMBL8969882 | 0.87 | CNR2 (0.34) | RARBENPP2 | |
| SCHEMBL8969591 | 0.87 | CNR2 (0.34) | RARBENPP2 | |
| SCHEMBL8969744 | 0.87 | CNR2 (0.33) | RARBS1PR1PTPN11 | |
| SCHEMBL8970864 | 0.86 | RARB (0.37) | RARBENPP2S1PR1S1PR3S1PR2 | |
| SCHEMBL8969598 | 0.86 | S1PR1 (0.33) | RARBS1PR1PTPN11 | |
| SCHEMBL9494734 | 0.86 | RARB (0.55) | RARBS1PR1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |