Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969201 | 0.91 | RARB (0.38) | RARBS1PR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8969570 | 0.91 | SLC6A2 (0.39) | RARBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8969819 | 0.89 | RARB (0.42) | RARBS1PR1GBA1LCTUGCG | |
| SCHEMBL8969304 | 0.88 | CNR2 (0.34) | SLC6A2SLC6A4SLC6A3CNR1CNR2 | |
| SCHEMBL8969298 | 0.88 | CNR2 (0.34) | SLC6A2SLC6A4SLC6A3CNR1CNR2 | |
| SCHEMBL8969239 | 0.87 | CNR2 (0.35) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8969535 | 0.86 | RARB (0.39) | RARBS1PR1MEN1HTTKMT2A | |
| SCHEMBL8969709 | 0.84 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3CNR1CNR2 | |
| SCHEMBL9494734 | 0.83 | RARB (0.55) | RARBS1PR1MEN1HTTKMT2A | |
| SCHEMBL8944200 | 0.82 | FPR2 (0.35) | RARBSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |