Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968908 | 0.90 | ACHE (0.46) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8969580 | 0.90 | ACHE (0.49) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8968995 | 0.89 | ACHE (0.45) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8968417 | 0.89 | ACHE (0.48) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8969642 | 0.84 | ACHE (0.48) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8969047 | 0.82 | ACHE (0.43) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8969183 | 0.82 | ACHE (0.43) | ACHEMEN1HTTRECQLKMT2A | |
| SCHEMBL8969467 | 0.80 | ACHE (0.47) | ACHEMEN1HTTKMT2A | |
| SCHEMBL8968711 | 0.80 | ACHE (0.47) | ACHEMEN1HTTKMT2A | |
| SCHEMBL8969738 | 0.79 | ACHE (0.46) | ACHEMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |