Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969565 | 0.77 | HTR6 (0.43) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969078 | 0.76 | HTR6 (0.42) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8968935 | 0.75 | HTR6 (0.45) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8968885 | 0.73 | PARP1 (0.42) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8968450 | 0.71 | HTR6 (0.44) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969697 | 0.70 | HTR6 (0.46) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL25414413 | 0.70 | PIK3CD (0.36) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8968396 | 0.70 | HTR6 (0.47) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8968971 | 0.70 | PARP1 (0.42) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969057 | 0.70 | PARP1 (0.42) | HTR6KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |