SCHEMBL8969893

SCHEMBL8969893

CCOc1ccc(-c2ccc(-c3ccc(/C=C/C4CCC(C)CC4)c(F)c3)cc2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.34
KDM1A O60341 2/20 0.31
FGFR2 P21802 2/20 0.31
FGFR1 P11362 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970117 0.81
SCHEMBL10303414 0.81 FGFR2 (0.36) NAAAKDM1AFGFR2FGFR1FFAR4
SCHEMBL8969770 0.81 GRIN1 (0.34) FGFR2FGFR1FFAR4
SCHEMBL9020651 0.79 NAAA (0.36) NAAAKDM1AFGFR2FGFR1FFAR4
SCHEMBL10164782 0.79
SCHEMBL8970688 0.78 NAAA (0.53) NAAAFGFR2FGFR1
SCHEMBL13264330 0.77 FGFR2 (0.39) NAAAKDM1AFGFR2FGFR1
SCHEMBL10303411 0.77 FGFR2 (0.39) NAAAKDM1AFGFR2FGFR1
SCHEMBL8934438 0.77 NAAA (0.34) NAAAKDM1AFGFR2FGFR1FFAR4
SCHEMBL11953527 0.77 FFAR4 (0.39) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed