Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14209863 | 0.82 | MAPK1 (0.38) | MAPK1HRH3 | |
| SCHEMBL8970005 | 0.81 | MAPK1 (0.33) | MAPK1HRH3 | |
| SCHEMBL9033901 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL9033895 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL9033905 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL25286574 | 0.79 | BTK (0.43) | GRM2BTKMAPK1HRH3GRM3 | |
| SCHEMBL1297403 | 0.79 | BTK (0.43) | GRM2BTKMAPK1HRH3GRM3 | |
| SCHEMBL1297008 | 0.79 | BTK (0.43) | GRM2BTKMAPK1HRH3GRM3 | |
| SCHEMBL6162465 | 0.79 | BTK (0.43) | GRM2BTKMAPK1HRH3GRM3 | |
| SCHEMBL25245251 | 0.79 | BTK (0.43) | GRM2BTKMAPK1HRH3GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |