Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 15/20 | 0.86 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970102 | 1.00 | SLC29A1 (0.86) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL6761745 | 0.93 | SLC29A1 (1.00) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL31462888 | 0.93 | SLC29A1 (1.00) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL8971093 | 0.83 | SLC29A1 (0.67) | SLC29A1ADORA3 | |
| SCHEMBL8971105 | 0.83 | SLC29A1 (0.67) | SLC29A1ADORA3 | |
| SCHEMBL8971138 | 0.83 | SLC29A1 (0.62) | SLC29A1ADORA3 | |
| SCHEMBL8971129 | 0.83 | SLC29A1 (0.62) | SLC29A1ADORA3 | |
| SCHEMBL8971796 | 0.83 | ADORA3 (0.62) | SLC29A1ADORA3 | |
| SCHEMBL6760626 | 0.82 | SLC29A1 (0.81) | SLC29A1LMNARAB9ASTAT6ADORA3 | |
| SCHEMBL24233629 | 0.81 | ADORA2A (0.80) | SLC29A1LMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0671410-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | disclosed |
| US-5420115-A | Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides | BURROUGHS WELLCOME CO. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0417999-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |