Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971560 | 0.82 | TSHR (0.38) | TSHRCYP1A2KCNN4MAPK1CYP3A4 | |
| SCHEMBL3257736 | 0.79 | KCNN4 (0.33) | TSHRKCNN4MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL16459018 | 0.78 | ALDH1A1 (0.42) | KCNN4MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL12814997 | 0.78 | ESR1 (0.42) | TSHRKCNN4MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL7584605 | 0.78 | KCNN4 (0.32) | TSHRKCNN4MAPK1ALDH1A1 | |
| SCHEMBL7049970 | 0.76 | KCNN4 (0.31) | TSHRKCNN4MAPK1ALDH1A1 | |
| SCHEMBL6357129 | 0.76 | KCNN4 (0.31) | TSHRKCNN4MAPK1ALDH1A1 | |
| SCHEMBL7196918 | 0.76 | KCNN4 (0.31) | TSHRKCNN4MAPK1ALDH1A1 | |
| SCHEMBL4652614 | 0.76 | TAAR1 (0.33) | TSHRKCNN4MAPK1ALDH1A1 | |
| SCHEMBL6850857 | 0.76 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492974-A | Process for preparing polymer bound metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492973-A | Polymer bound ligands | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492978-A | Process for preparing catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492985-A | Polymerization processes | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492975-A | Polymer bound metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0690076-A1 | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5473020-A | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-12-05 | — | — | US | disclosed |