Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355962 | 0.81 | KDM4E (0.53) | KDM4ELMNAALDH1A1POLBCDK2 | |
| SCHEMBL17701245 | 0.69 | F2RL1 (0.31) | — | |
| SCHEMBL15470591 | 0.68 | CCR1 (0.67) | KDM4ELMNAALDH1A1POLBCDK2 | |
| SCHEMBL14970145 | 0.68 | KDM4E (0.61) | KDM4ELMNAALDH1A1POLBRAB9A | |
| SCHEMBL9594088 | 0.68 | HSP90AA1 (0.37) | CDK2MAPT | |
| SCHEMBL558888 | 0.68 | KDM4E (0.58) | KDM4ELMNAALDH1A1POLBRAB9A | |
| SCHEMBL543415 | 0.68 | RAB9A (0.50) | KDM4ELMNAALDH1A1RAB9AMAPT | |
| SCHEMBL557963 | 0.67 | CYP1A1 (0.38) | ALDH1A1DYRK1BDYRK1AGAAMAPT | |
| SCHEMBL5165179 | 0.67 | CDK4 (0.45) | KDM4ELMNAALDH1A1POLBCDK2 | |
| SCHEMBL316318 | 0.67 | KDM4E (0.33) | KDM4ELMNAALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |