Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.62 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 2/20 | 0.58 |
| ▸ | AHCY | P23526 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.56 |
| ▸ | MARS1 | P56192 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585105 | 0.92 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL8970112 | 0.90 | EHMT1 (0.52) | NT5EEHMT1PRKACAAHCYRXFP1 | |
| SCHEMBL10587627 | 0.89 | EHMT1 (0.71) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL10587414 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL5561909 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL5364744 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL1669299 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL14696397 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL12800893 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 | |
| SCHEMBL5375737 | 0.88 | EHMT1 (0.69) | EHMT1PRKACAAHCYRXFP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0671410-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | disclosed |
| US-5420115-A | Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides | BURROUGHS WELLCOME CO. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0417999-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |