Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.63 |
| ▸ | NT5E | P21589 | 3/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | AHCY | P23526 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637468 | 0.91 | EHMT1 (0.76) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL9231760 | 0.91 | EHMT1 (0.76) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL10865966 | 0.90 | EHMT1 (0.74) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL1920531 | 0.90 | EHMT1 (0.74) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL8970121 | 0.89 | EHMT1 (0.56) | EHMT1NT5ERXFP1AHCYADORA1 | |
| SCHEMBL29936475 | 0.88 | EHMT1 (0.74) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL8671033 | 0.88 | EHMT1 (0.74) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL8671037 | 0.88 | EHMT1 (0.74) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 | |
| SCHEMBL1582614 | 0.88 | EHMT1 (0.62) | EHMT1RXFP1AHCYADORA1ADORA3 | |
| SCHEMBL10590849 | 0.87 | EHMT1 (0.66) | EHMT1RXFP1AHCYADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0671410-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | disclosed |
| US-5420115-A | Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides | BURROUGHS WELLCOME CO. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0417999-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |