Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 18/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965800 | 0.89 | PRKCQ (0.70) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970422 | 0.86 | PRKCQ (0.56) | PRKCQPRKCAPRKCD | |
| SCHEMBL11993705 | 0.86 | PRKCQ (0.56) | PRKCQPRKCAPRKCD | |
| SCHEMBL11993698 | 0.80 | PRKCQ (0.79) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970582 | 0.79 | PRKCQ (0.60) | PRKCQPRKCAPRKCDGRM5 | |
| SCHEMBL11993707 | 0.79 | PRKCQ (0.60) | PRKCQPRKCAPRKCDGRM5 | |
| SCHEMBL8965670 | 0.76 | PRKCQ (0.70) | PRKCQPRKCAPRKCD | |
| SCHEMBL8965751 | 0.75 | PRKCQ (0.67) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970209 | 0.74 | PRKCQ (0.62) | PRKCQPRKCAPRKCD | |
| SCHEMBL8179345 | 0.70 | PRKCQ (0.64) | PRKCQPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188071-B2 | Amino substituted pyridines as potent kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |