Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12759837 | 0.93 | ESR1 (0.33) | FFAR4ESR1FPR2GRIN1GRIN2B | |
| SCHEMBL8970844 | 0.91 | GRIN1 (0.32) | ESR1FPR2GRIN1GRIN2B | |
| SCHEMBL8970556 | 0.91 | GRIN1 (0.32) | ESR1FPR2GRIN1GRIN2B | |
| SCHEMBL8970531 | 0.91 | GRIN1 (0.32) | ESR1FPR2GRIN1GRIN2B | |
| SCHEMBL12759921 | 0.90 | ESR1 (0.33) | FFAR4ESR1FPR2GRIN1GRIN2B | |
| SCHEMBL12759910 | 0.89 | CHRM2 (0.34) | FFAR4 | |
| SCHEMBL13000851 | 0.88 | NAAA (0.34) | FFAR4S1PR1FPR2GRIN1GRIN2B | |
| SCHEMBL8932755 | 0.88 | FFAR4 (0.39) | FFAR4FFAR1PPARDS1PR1S1PR3 | |
| SCHEMBL12759873 | 0.87 | CHRM2 (0.33) | FPR2 | |
| SCHEMBL8970564 | 0.87 | SLC6A2 (0.35) | FFAR4HMOX1FFAR1PPARDFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |