SCHEMBL8970486

SCHEMBL8970486

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(N(C)C(=O)NS(=O)(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.78
PPARG P37231 1/20 0.78
RXFP1 Q9HBX9 1/20 0.78
NR2E3 Q9Y5X4 1/20 0.78
NCOR2 Q9Y618 1/20 0.78
CA12 O43570 4/20 0.65
CA9 Q16790 4/20 0.65
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
CA5A P35218 2/20 0.65
CA7 P43166 2/20 0.65
CA13 Q8N1Q1 2/20 0.65
CA14 Q9ULX7 2/20 0.65
TP53 P04637 1/20 0.65
LMNA P02545 3/20 0.64
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
ALDH1A1 P00352 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418168 0.86 PPARG (0.82) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL1928662 0.86 CA12 (0.85) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL6243996 0.86 CA12 (0.85) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL8970207 0.85 LMNA (0.62) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL5186659 0.82 LMNA (0.58) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL1395600 0.82 CA12 (0.78) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL6297211 0.82 PPARG (0.74) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL5517478 0.81 CA12 (0.72) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL6470672 0.80 CA12 (0.76) RAB9APPARGRXFP1NR2E3NCOR2
SCHEMBL20568276 0.80 CA12 (0.76) RAB9APPARGRXFP1NR2E3NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed