Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970543 | 1.00 | KMT2A (0.42) | KMT2AKDM4EMEN1CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL8971298 | 0.98 | KMT2A (0.41) | KMT2AKDM4EMEN1CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL8971296 | 0.98 | KMT2A (0.41) | KMT2AKDM4EMEN1CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL8970540 | 0.80 | GAA (0.48) | KMT2AKDM4EMEN1CYP2D6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8970545 | 0.80 | GAA (0.48) | KMT2AKDM4EMEN1CYP2D6L3MBTL1 | |
| SCHEMBL6099595 | 0.80 | KMT2A (0.37) | KMT2AKDM4EMEN1CYP2D6LMNA | |
| SCHEMBL6099589 | 0.80 | KMT2A (0.37) | KMT2AKDM4EMEN1CYP2D6LMNA | |
| SCHEMBL26210274 | 0.69 | LPO (0.38) | KMT2AMEN1L3MBTL1ALDH1A1POLB | |
| SCHEMBL2457805 | 0.68 | KDM4E (0.47) | KMT2AKDM4EMEN1CYP2D6L3MBTL1 | |
| SCHEMBL2457803 | 0.68 | KDM4E (0.47) | KMT2AKDM4EMEN1CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552427-A | ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0656210-A1 | Imidazole derivatives as glutaminose inhibitors | Takeda Chemical Industries, Ltd. (JP) | 1995-06-07 | — | — | EP | disclosed |