SCHEMBL8970557

SCHEMBL8970557

CN(C)c1cccc(C(=O)Nc2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 4/20 0.70
MAPT P10636 5/20 0.62
RAB9A P51151 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
HTT P42858 1/20 0.62
HDAC6 Q9UBN7 2/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
TP53 P04637 2/20 0.59
NPC1 O15118 2/20 0.59
KCNK9 Q9NPC2 2/20 0.59
BCHE P06276 1/20 0.58
ACHE P22303 1/20 0.58
KMT2A Q03164 5/20 0.57
POLB P06746 2/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
ALOX15 P16050 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7745692 0.90 KCNK3 (0.80) KCNK3MAPTRAB9ASMN1; SMN2TP53
SCHEMBL10428582 0.86 MAPT (0.62) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL3707848 0.86 MAPT (0.58) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL12763862 0.86 KCNK3 (0.75) KCNK3MAPTRAB9AHTTHDAC6
SCHEMBL27749505 0.86 MAPT (0.62) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL6816845 0.86 MAPT (0.62) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL15482247 0.85 HDAC6 (0.63) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL10294866 0.85 KMT2A (0.59) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL6153325 0.85 MAPT (0.60) KCNK3MAPTRAB9ASMN1; SMN2HTT
SCHEMBL6782639 0.85 BTK (0.64) KCNK3MAPTRAB9ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed
US-4920220-A FOR PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY CORPORATION (US) 1990-04-24 US disclosed
EP-0316277-A2 Chromogeneous 1-heterocyclically substituted 2,4-benzoxazines CIBA-GEIGY AG (CH) 1989-05-17 EP disclosed