Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.80 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459923 | 0.91 | KCNK3 (0.71) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL8970557 | 0.90 | KCNK3 (0.70) | KCNK3KCNK9MEN1KMT2ASIRT1 | |
| SCHEMBL7606555 | 0.88 | KCNK3 (0.68) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL11433655 | 0.86 | KCNK3 (0.65) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL12764313 | 0.86 | KCNK3 (0.80) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL95091 | 0.86 | KCNK3 (0.65) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL31686015 | 0.85 | KCNK3 (0.71) | KCNK3KCNK9MEN1KMT2ASIRT1 | |
| SCHEMBL10294800 | 0.85 | KCNK3 (0.63) | KCNK3KCNK9MEN1KMT2ASIRT1 | |
| SCHEMBL10294109 | 0.85 | KCNK3 (0.63) | KCNK3KCNK9MEN1KMT2ASIRT1 | |
| SCHEMBL7292759 | 0.85 | RAB9A (0.74) | KCNK3KCNK9MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129075-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2001-09-05 | — | — | EP | claimed |
| WO-2000027820-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | claimed |
| EP-1129075-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027820-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | disclosed |
| EP-0254858-B1 | CHROMOGENIC 3,1-BENZOXAZINE | BAYER AG (DE) | 1990-10-31 | — | — | EP | disclosed |
| US-4831141-A | PRESSURE SENSITIVE RECORDING | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0254858-A2 | Chromogenic 3,1-benzoxazine | BAYER AG (DE) | 1988-02-03 | — | — | EP | disclosed |
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |
| EP-0042357-A2 | Azo dyes, their preparation and use | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| US-4240959-A | FOR ACRYLONITRILE POLYMER OR COPOLYMER FIBERS; FASTNESS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-12-23 | — | — | US | disclosed |