Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30039183 | 0.85 | CA2 (0.52) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4895002 | 0.84 | CA2 (0.56) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11659316 | 0.83 | CA2 (0.54) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8970706 | 0.81 | CA2 (0.52) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL14603472 | 0.80 | CA2 (0.47) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5280803 | 0.80 | GLRA3 (0.48) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1597366 | 0.79 | CA2 (0.61) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8772288 | 0.79 | CA2 (0.61) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11586001 | 0.79 | CA2 (0.50) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11407074 | 0.79 | CA2 (0.50) | CA2CA1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703239-A1 | Aminomethylphosphonic and aminomethylphosphinic acids derivatives and their use in the treatment of degenerative articular diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-27 | — | — | EP | disclosed |
| EP-0700923-A1 | Stabilised dithiophosphoric acid disulphides | RHEIN CHEMIE RHEINAU GmbH (DE) | 1996-03-13 | — | — | EP | disclosed |