Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | ACR | P10323 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522875 | 1.00 | RARB (0.70) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8971229 | 1.00 | RARB (0.70) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9057790 | 0.97 | RARB (0.70) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9477456 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9457316 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9471276 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8376750 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9478118 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9182247 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL5355713 | 0.94 | NPC1 (0.74) | RARBNPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0427166-B1 | Ester compounds and liquid crystal compositions containing the same | JAPAN ENERGY CORP (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| US-5211879-A | ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | NIPPON MINING CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0427166-A1 | Ester compounds and liquid crystal compositions containing the same | JAPAN ENERGY CORPORATION (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |