Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.74 |
| ▸ | RELA | Q04206 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | RARB | P10826 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | ACR | P10323 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471276 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9457316 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9476073 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9478118 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8376750 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL5355713 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9477456 | 1.00 | NPC1 (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL30477070 | 0.97 | NPC1 (0.71) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL12732828 | 0.95 | NPC1 (0.81) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL2449749 | 0.95 | NPC1 (0.81) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315996-B1 | Optically active compound, process for producing same and liquid crystal composition containing same | CANON KK (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0347944-B1 | Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same | CANON KK (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0237007-B1 | Fluoroalkane derivative and liquid crystal composition | CANON KK (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0267585-B1 | FLUOROALKANE DERIVATIVE, ITS COMPOSITION AND LIQUID CRYSTAL DEVICE USING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5075031-A | Prevent reverse domain | CANON KABUSHIKI KAISHA (JP) | 1991-12-24 | — | — | US | disclosed |
| US-4917817-A | Optical active compound, process for producing same and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0301511-A1 | Optically active compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-02-01 | — | — | EP | disclosed |
| EP-0300497-A1 | Optically active compound, process for producing same and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-01-25 | — | — | EP | disclosed |
| EP-0267585-A2 | Fluoroalkane derivative, its composition and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1988-05-18 | — | — | EP | disclosed |
| EP-0255962-A2 | Optically active mesomorphic compound | CANON KABUSHIKI KAISHA (JP) | 1988-02-17 | — | — | EP | disclosed |
| EP-0237007-A2 | Fluoroalkane derivative and liquid crystal composition | CANON KABUSHIKI KAISHA (JP) | 1987-09-16 | — | — | EP | disclosed |