Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224618 | 1.00 | NPC1 (0.47) | NPC1RAB9AMAPTSTAT3ATM | |
| SCHEMBL9507636 | 1.00 | NPC1 (0.47) | NPC1RAB9AMAPTSTAT3ATM | |
| SCHEMBL9506149 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9507596 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9507613 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9506292 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9506321 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9506166 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9510040 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9506138 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0292954-B1 | USE OF OPTICALLY ACTIVE OXIRANE-2-CARBOXYLIC ACID ESTERS AS DOPANTS IN LIQUID CRYSTAL MIXTURES CONTAINING THEM AND NEW OPTICALLY ACTIVE OXIRANE-2-CARBOXYLIC ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-05 | — | — | EP | disclosed |
| EP-0538292-A1 | METHOD OF SEPARATING 2-ALKYLTHIO-5-PHENYLPYRIMIDINES FROM REACTION MIXTURES BY EXTRACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000969-A1 | METHOD OF SEPARATING 2-ALKYLTHIO-5-PHENYLPYRIMIDINES FROM REACTION MIXTURES BY EXTRACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-23 | — | — | WO | disclosed |
| US-4988459-A | Electrooptic switches or display | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0334925-A1 | FERROELECTRIC LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989003416-A1 | FERROELECTRIC LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-04-20 | — | — | WO | disclosed |
| EP-0292954-A2 | Use of optically active oxirane-2-carboxylic acid esters as dopants in liquid crystal mixtures containing them and new optically active oxirane-2-carboxylic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |