SCHEMBL8970912

SCHEMBL8970912

COO[C@]1(OC)[C@H](O)[C@@H](CO)O[C@]1(n1cnc2c(O)ncnc21)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 3/20 0.36
ADORA1 P30542 4/20 0.34
TYMP P19971 1/20 0.33
ADORA3 P0DMS8 3/20 0.32
ADORA2A P29274 2/20 0.32
ADORA2B P29275 1/20 0.32
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.31
NPY1R P25929 1/20 0.31
HTT P42858 1/20 0.31
NPY2R P49146 1/20 0.31
RAB9A P51151 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10380926 0.91 ADORA1 (0.44) SLC29A1ADORA1ADORA3ADORA2AADORA2B
SCHEMBL3813881 0.85 ADORA1 (0.46) SLC29A1ADORA1ADORA3ADORA2AADORA2B
SCHEMBL28992806 0.82 SLC29A1 (0.37) SLC29A1ADORA1TYMPADORA3ADORA2A
SCHEMBL10481813 0.79 ADORA1 (0.39) ADORA1ADORA3ADORA2AADORA2B
SCHEMBL27446941 0.77 ADORA1 (0.45) SLC29A1ADORA1ADORA3ADORA2AADORA2B
SCHEMBL6382374 0.75 SLC28A1 (0.35) SLC29A1
SCHEMBL3810729 0.75 HPGD (0.42) ADORA3NFKB1TSHRLMNAALDH1A1
SCHEMBL8970900 0.73 SLC29A1 (0.37) SLC29A1ADORA1ADORA3ADORA2AADORA2B
SCHEMBL9773470 0.73 SLC29A1 (0.31) SLC29A1ADORA1
SCHEMBL5954790 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525719-A N-protected-2'-O-methyl-and N-protected-3'-O-methyl-ribonucleosides and their phosphoramidite derivatives CHEMGENES CORPORATION (US) 1996-06-11 US disclosed