Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381790 | 0.91 | ADORA1 (0.43) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL10890138 | 0.81 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2BNFKB1 | |
| SCHEMBL1068569 | 0.80 | ADORA1 (0.44) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL9705275 | 0.79 | ADORA3 (0.46) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5859569 | 0.78 | PI4KA (0.43) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL9752462 | 0.77 | LMNA (0.38) | SLC29A1ADORA2AADORA2B | |
| SCHEMBL674400 | 0.74 | ADORA1 (0.48) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6852710 | 0.74 | ADORA1 (0.48) | SLC29A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5954785 | 0.74 | ADORA2A (0.31) | ADORA2AADORA2B | |
| SCHEMBL6756343 | 0.73 | RNASE1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525719-A | N-protected-2'-O-methyl-and N-protected-3'-O-methyl-ribonucleosides and their phosphoramidite derivatives | CHEMGENES CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |