Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971237 | 1.00 | SIGMAR1 (0.58) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9090508 | 0.98 | SIGMAR1 (0.57) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970701 | 0.95 | SIGMAR1 (0.56) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8971350 | 0.94 | SLC6A4 (0.54) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9092165 | 0.94 | SIGMAR1 (0.57) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9092879 | 0.92 | SIGMAR1 (0.60) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970731 | 0.92 | SLC6A4 (0.57) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8971041 | 0.91 | SLC6A4 (0.59) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970816 | 0.89 | SIGMAR1 (0.60) | SIGMAR1HTR1ALMNAALOX15TSHR | |
| SCHEMBL8970633 | 0.89 | SIGMAR1 (0.60) | SIGMAR1HTR1ASLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490560-B1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZET (HU) | 1996-03-20 | — | — | EP | claimed |
| EP-0490560-B1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZET (HU) | 1996-03-20 | — | — | EP | disclosed |
| US-5225416-A | 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES USEFUL FOR IMPROVING CEREBRAL BLOOD CIRCULATION | RICHTER GEDEON VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-07-06 | — | — | US | disclosed |
| EP-0490560-A1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-06-17 | — | — | EP | disclosed |