Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629735 | 0.84 | TYR (0.44) | TYRACACBPTGS1PTGS2LMNA | |
| SCHEMBL765451 | 0.81 | TYR (0.41) | TYRACACBPTGS1PTGS2LMNA | |
| SCHEMBL29487262 | 0.77 | TSHR (0.61) | TYRACACBPTGS1PTGS2LMNA | |
| SCHEMBL1148 | 0.77 | TSHR (0.61) | TYRACACBPTGS1PTGS2LMNA | |
| SCHEMBL27309457 | 0.77 | TRPA1 (0.48) | PTGS1TSHREPHX1TRPA1 | |
| SCHEMBL9744706 | 0.76 | SMN1; SMN2 (0.41) | TYRESR1TSHRIDO1ESR2 | |
| SCHEMBL28245936 | 0.76 | TYR (0.47) | TYRACACBPTGS1PTGS2LMNA | |
| SCHEMBL1219827 | 0.75 | ESR1 (0.45) | ACACBPTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL20610522 | 0.75 | ESR1 (0.45) | ACACBPTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL10078239 | 0.74 | IDO1 (0.46) | TYRACACBTSHRIDO1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506051-A | LAMINATE HAVING RADIATION-CURED URETHANE ACRYLATE OR POLYETHER ACRYLATE OLIGOMERS; ELONGATION, TOUGHNESS | NICOLECTRONIX LTD. LABORATORIES (IL) | 1996-04-09 | — | — | US | disclosed |