Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.71 |
| ▸ | FNTB | P49356 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266283 | 1.00 | FNTA (0.71) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL9003093 | 0.89 | FNTA (0.72) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL9003038 | 0.88 | TACR1 (0.65) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL8971328 | 0.86 | TACR1 (0.59) | FNTAFNTBKMT2AMEN1TACR1 | |
| Hydrochloric Acid SCHEMBL9268749 | 0.85 | TACR1 (0.59) | FNTAFNTBKMT2AMEN1TACR1 | |
| Hydrochloric Acid SCHEMBL9003020 | 0.85 | TACR1 (0.59) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL9269132 | 0.84 | TACR1 (0.59) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL9270016 | 0.84 | TACR1 (0.59) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL9003180 | 0.84 | FNTA (0.53) | FNTAFNTBKMT2AMEN1TACR1 | |
| SCHEMBL8971592 | 0.84 | FNTA (0.53) | FNTAFNTBKMT2AMEN1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586490-B1 | DERIVATIVES OF PERHYDROISOINDOL, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE POULENC RORER SA (FR) | 1996-03-20 | — | — | EP | claimed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | claimed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |