Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | FNTA | P49354 | 6/20 | 0.56 |
| ▸ | FNTB | P49356 | 6/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003165 | 0.89 | TACR1 (0.66) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL9266283 | 0.88 | FNTA (0.71) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8970958 | 0.88 | FNTA (0.71) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL17238244 | 0.82 | TACR1 (0.67) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL29407214 | 0.82 | TACR1 (0.67) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL4296689 | 0.82 | TACR1 (0.67) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL29907325 | 0.82 | TACR1 (0.67) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL4349316 | 0.78 | TACR1 (1.00) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8460496 | 0.78 | TACR1 (1.00) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL7551020 | 0.78 | TACR1 (1.00) | TACR1MEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |