SCHEMBL8971042

SCHEMBL8971042

CC(Cl)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.43
SLC22A2 O15244 1/20 0.38
SLC22A3 O75751 1/20 0.38
HTR2A P28223 1/20 0.38
POLB P06746 3/20 0.36
ACHE P22303 3/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
KMT2A Q03164 2/20 0.34
BCHE P06276 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837267 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL3922127 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL8970174 0.79 TSHR (0.39) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL14815616 0.76 GPR3 (0.43) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL12815279 0.73 GPR3 (0.40) GPR3HTR2APOLBACHECHRM2
SCHEMBL8970933 0.73 TSHR (0.42) GPR3SLC22A2SLC22A3HTR2APOLB
Chloromethane SCHEMBL8162040 0.70 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
Chloromethane SCHEMBL8155580 0.70 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL28358252 0.70 GPR3 (0.41) GPR3SLC22A2SLC22A3HTR2APOLB
Chloromethane SCHEMBL8147940 0.70 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492974-A Process for preparing polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492978-A Process for preparing catalyst system PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492973-A Polymer bound ligands PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492985-A Polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492975-A Polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
EP-0690076-A1 Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-01-03 EP disclosed
US-5473020-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-12-05 US disclosed