SCHEMBL8971094

SCHEMBL8971094

Cn1nnc(S)c1-c1cccc(NC(=O)Oc2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.51
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 8/20 0.43
MAPT P10636 5/20 0.43
GAA P10253 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43
NPC1 O15118 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 3/20 0.42
FAAH O00519 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
PORCN Q9H237 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971107 0.82 SMN1; SMN2 (0.50) CYP1A2KMT2AALDH1A1MAPTGAA
SCHEMBL4437613 0.80 CYP1A2 (0.53) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL1569274 0.76 CYP1A2 (0.68) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL23240038 0.76 CYP1A2 (0.54) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL29716418 0.76 CYP1A2 (0.54) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL6274455 0.74 CCR3 (0.47) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL23213539 0.74 CYP1A2 (0.55) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL8048626 0.73 CYP1A2 (0.76) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL5383938 0.73 KMT2A (0.51) CYP1A2BCHEACHEKMT2AALDH1A1
SCHEMBL14139652 0.72 CYP1A2 (0.55) CYP1A2BCHEACHEKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426112-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-02-28 EP disclosed
US-5151357-A Light sensitive elements with phosphonate groups FUJI PHOTO FILM CO., LTD. (JP) 1992-09-29 US disclosed
EP-0426112-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-05-08 EP disclosed