Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725147 | 0.83 | HRH3 (0.41) | HRH3AKR1C3 | |
| SCHEMBL3532818 | 0.77 | HRH3 (0.39) | KDM4EOPRM1HRH3MEN1KMT2A | |
| SCHEMBL3532821 | 0.77 | HRH3 (0.39) | KDM4EOPRM1HRH3 | |
| SCHEMBL23612752 | 0.77 | HRH3 (0.41) | KDM4EOPRM1HRH3 | |
| SCHEMBL17190311 | 0.76 | HRH3 (0.36) | HRH3AKR1C3 | |
| SCHEMBL20328001 | 0.76 | KDM4E (0.50) | KDM4EGPR183 | |
| SCHEMBL21414346 | 0.74 | KDM4E (0.41) | KDM4EOPRM1HRH3GPR183 | |
| SCHEMBL24040238 | 0.74 | HRH3 (0.40) | OPRM1HRH3 | |
| SCHEMBL29010533 | 0.73 | CPB2 (0.33) | AKR1C3 | |
| SCHEMBL28718955 | 0.73 | CPB2 (0.33) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |