Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970702 | 1.00 | SIGMAR1 (0.58) | SIGMAR1HTR1ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8970635 | 0.95 | SIGMAR1 (0.56) | SIGMAR1HTR1ASLC6A4SLC6A3 | |
| SCHEMBL16053652 | 0.94 | SIGMAR1 (0.57) | SIGMAR1HTR1ASLC6A4SLC6A3 | |
| SCHEMBL8971350 | 0.94 | SLC6A4 (0.54) | SIGMAR1HTR1ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11793198 | 0.92 | SIGMAR1 (0.56) | SIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL8971631 | 0.91 | SLC6A4 (0.56) | SIGMAR1HTR1ASLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL8970739 | 0.90 | SLC6A4 (0.55) | SIGMAR1HTR1ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8970816 | 0.89 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL8970920 | 0.89 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL8971378 | 0.89 | SIGMAR1 (0.60) | SIGMAR1HTR1ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490560-B1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZET (HU) | 1996-03-20 | — | — | EP | claimed |