Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 7/20 | 0.56 |
| ▸ | CES2 | O00748 | 6/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27925052 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28407988 | 1.00 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11785134 | 0.98 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL30648522 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28761872 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2762272 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL29286711 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL578126 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL27757634 | 0.90 | TSHR (0.63) | TSHRDAONAPRTSRD5A2ALDH1A1 | |
| Benzoic Acid SCHEMBL3948196 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731924-A | Environmental protection type PVC plastisol and application thereof | CHANGZHOU KANGBAO PAINT CHEMICAL CO LTD | 2012-10-17 | — | — | CN | claimed |
| US-20120231170-A1 | VAPOR PERMEABLE BARRIER COATING APPLICABLE AT LOW TEMPERATURE | VERIFI LLC | 2012-09-13 | — | — | US | claimed |
| WO-2011066160-A1 | VAPOR PERMEABLE BARRIER COATING APPLICABLE AT LOW TEMPERATURE | W.R. GRACE & CO.-CONN. (US) | 2011-06-03 | — | — | WO | claimed |
| US-20250138377-A1 | OPTICALLY TRANSPARENT POLYMERIC ION CONDUCTIVE LAYERS FOR ELECTROCHROMIC DEVICES | Mativ Luxembourg (LU) | 2025-05-01 | — | — | US | disclosed |
| CN-116636063-A | Optically transparent polymer electrolyte membrane | 斯瓦蒙卢森堡公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-107417818-A | It is a kind of for the catalytic component of olefinic polymerization, preparation method and catalyst | 北京利和知信科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-8748528-B2 | Vapor permeable barrier coating applicable at low temperature | W. R. GRACE & CO.-CONN. (US) | 2014-06-10 | — | — | US | disclosed |
| CN-102731924-A | Environmental protection type PVC plastisol and application thereof | CHANGZHOU KANGBAO PAINT CHEMICAL CO LTD | 2012-10-17 | — | — | CN | disclosed |
| US-20120231170-A1 | VAPOR PERMEABLE BARRIER COATING APPLICABLE AT LOW TEMPERATURE | VERIFI LLC | 2012-09-13 | — | — | US | disclosed |
| US-20120083569-A1 | Polymerizable Compounds, Curable Compositions And Methods | KUNSTSTOFF-UND FARBEN-GESELLSCHAFT MBH (DE) | 2012-04-05 | — | — | US | disclosed |
| WO-2011066160-A1 | VAPOR PERMEABLE BARRIER COATING APPLICABLE AT LOW TEMPERATURE | W.R. GRACE & CO.-CONN. (US) | 2011-06-03 | — | — | WO | disclosed |