Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.74 |
| ▸ | CES1 | P23141 | 7/20 | 0.61 |
| ▸ | CES2 | O00748 | 6/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29286711 | 1.00 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL578126 | 1.00 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9861287 | 0.97 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL10948080 | 0.95 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11288243 | 0.93 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2400344 | 0.92 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28693411 | 0.92 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28601772 | 0.92 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9705228 | 0.92 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL6573567 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505185-A | PAF supported ruthenium catalyst and preparation method and application thereof | 南昌大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119430458-A | Preparation method of composite material for ozone photocatalytic synergistic degradation of ibuprofen in sewage | 北方工业大学 | 2025-02-14 | — | — | CN | claimed |
| CN-116122057-A | High-strength cold-resistant textile for aerospace use and manufacturing method thereof | 西京学院 | 2023-05-16 | — | — | CN | claimed |
| CN-115698168-A | Decorative panel and decorative floor covering composed of said panel | I4F许可有限责任公司 | 2023-02-03 | — | — | CN | claimed |
| CN-119505185-A | PAF supported ruthenium catalyst and preparation method and application thereof | 南昌大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-118290350-A | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113631535-B | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116874545-B | Coupling medicine, preparation method thereof and application of coupling medicine in preparation of medicine for treating rheumatoid arthritis synovium | 山东第一医科大学(山东省医学科学院) | 2024-01-05 | — | — | CN | disclosed |
| CN-116874545-A | Coupling medicine, preparation method thereof and application of coupling medicine in preparation of medicine for treating rheumatoid arthritis synovium | 山东第一医科大学(山东省医学科学院) | 2023-10-13 | — | — | CN | disclosed |
| EP-3597682-B1 | HETEROPHASIC PROPYLENE POLYMERIZATION MATERIAL AND PROPYLENE-BASED RESIN COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2023-09-27 | — | — | EP | disclosed |
| CN-112011129-B | Thermoplastic elastomer composition and method for producing same | 住友化学株式会社 | 2023-06-30 | — | — | CN | disclosed |
| CN-116122057-A | High-strength cold-resistant textile for aerospace use and manufacturing method thereof | 西京学院 | 2023-05-16 | — | — | CN | disclosed |
| CN-112011129-A | Thermoplastic elastomer composition and method for producing same | 住友化学株式会社 | 2020-12-01 | — | — | CN | disclosed |
| WO-2020217628-A1 | METHOD FOR PRODUCING PROPYLENE POLYMER | 住友化学株式会社 | 2020-10-29 | — | — | WO | disclosed |
| US-10800911-B2 | Heterophasic propylene polymerization material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-10-13 | — | — | US | disclosed |
| EP-3495420-A1 | HETEROPHASIC PROPYLENE POLYMERIC MATERIAL | Sumitomo Chemical Company, Limited (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-20190161605-A1 | HETEROPHASIC PROPYLENE POLYMERIZATION MATERIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-05-30 | — | — | US | disclosed |
| CN-108239191-A | A kind of alkoxyl magnesium carrier model catalyst component for olefin polymerization, catalyst and its application | 北京利和知信科技有限公司 | 2018-07-03 | — | — | CN | disclosed |
| US-20100316677-A1 | USE OF BAMBOO LEAF TOTAL FLAVONES IN THE PREPARATION OF MEDICINE AND HEALTH FOOD FOR PREVENTION AND TREATMENT OF PROSTATIC DISEASES | ZHEJIANG UNIVERSITY (HANGZHOU) LEAF BIO-TECHNOLOGY CO., LTD. (CN) | 2010-12-16 | — | — | US | disclosed |
| US-6136751-A | LOW MOLECULAR WEIGHT ORGANIC MATERIAL DISPERSED IN CARBAMATE-CONTAINING ACRYLIC GRAFT POLYMER MATRIX RESIN | RICOH COMPANY, LTD. (JP) | 2000-10-24 | — | — | US | disclosed |