Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8971588 | 0.90 | HTR4 (0.54) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8971888 | 0.88 | HTR4 (0.56) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8971037 | 0.88 | HTR4 (0.56) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8971367 | 0.87 | HTR4 (0.69) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8971616 | 0.86 | HTR4 (0.54) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3684761 | 0.86 | HTR4 (0.68) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8971612 | 0.85 | HTR4 (0.66) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8971911 | 0.85 | HTR4 (0.52) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7350017 | 0.83 | HTR4 (0.75) | HTR4MEN1KMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8971067 | 0.82 | HTR4 (0.57) | HTR4MEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |