Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775356 | 1.00 | GABRR1 (0.36) | GABRR1LMNAGABBR2GABBR1 | |
| SCHEMBL14151075 | 1.00 | GABRR1 (0.36) | GABRR1LMNAGABBR2GABBR1 | |
| SCHEMBL127505 | 0.79 | SLC6A2 (0.31) | — | |
| SCHEMBL18520334 | 0.77 | — | — | |
| SCHEMBL13478406 | 0.77 | — | — | |
| SCHEMBL6901467 | 0.76 | GABRR1 (0.45) | GABRR1LMNAGABBR2GABBR1 | |
| SCHEMBL12825053 | 0.71 | — | — | |
| SCHEMBL14224182 | 0.71 | — | — | |
| SCHEMBL381734 | 0.71 | — | — | |
| SCHEMBL436289 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567409-A | ADMINISTERING A TETRAPYRROLE CARBOXYLIC ACID IN SUFFICIENT QUANTITY TO ACCUMULATE IN ARTHRITIC LESION; APPLYING LIGHT TO CAUSE IT TO PRODUCE FLUORESCENCE | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| US-5430051-A | Photodynamic diagnosis and therapy of rheumatic diseases | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0629409-A1 | Tetrapyrrole carboxylic acid derivatives for diagnosis and/or therapy of arthritis | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5308861-A | Tetrapyrole compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0213272-B1 | NEW TETRAPYRROLE POLYAMINOMONOCARBOXYLIC ACID THERAPEUTIC AGENTS | Nippon Petrochemicals Co., Ltd. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0200218-B1 | TETRAPYRROLE THERAPEUTIC AGENTS | Nippon Petrochemicals Co., Ltd. (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4997639-A | Porphyrins | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0213272-A2 | New tetrapyrrole polyaminomonocarboxylic acid therapeutic agents | Nippon Petrochemicals Co., Ltd. (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0200218-A2 | Tetrapyrrole therapeutic agents | Nippon Petrochemicals Co., Ltd. (JP) | 1986-11-05 | — | — | EP | disclosed |