Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775674 | 0.91 | PTPN11 (0.41) | RARBPTPN11FAAHS1PR1S1PR3 | |
| SCHEMBL10780960 | 0.91 | PTPN11 (0.41) | RARBPTPN11FAAHS1PR1S1PR3 | |
| SCHEMBL10779322 | 0.90 | PTPN11 (0.40) | RARBPTPN11FAAHS1PR1S1PR3 | |
| SCHEMBL8971790 | 0.90 | PTPN11 (0.36) | PTPN11THRATHRBFAAHS1PR1 | |
| SCHEMBL8971419 | 0.90 | PTPN11 (0.36) | PTPN11THRATHRBFAAHS1PR1 | |
| SCHEMBL10776708 | 0.89 | PTPN11 (0.44) | RARBPTPN11THRATHRBFAAH | |
| SCHEMBL10779065 | 0.89 | PTPN11 (0.44) | RARBPTPN11THRATHRBFAAH | |
| SCHEMBL10780141 | 0.89 | S1PR1 (0.39) | RARBPTPN11FAAHS1PR1S1PR3 | |
| SCHEMBL8971133 | 0.89 | PTPN11 (0.38) | RARBPTPN11THRATHRBFAAH | |
| SCHEMBL10775870 | 0.89 | FFAR4 (0.40) | RARBPTPN11FAAHS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |