Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971790 | 1.00 | PTPN11 (0.36) | PTPN11THRATHRBS1PR5S1PR1 | |
| SCHEMBL8971133 | 0.93 | PTPN11 (0.38) | PTPN11THRATHRBS1PR5S1PR1 | |
| SCHEMBL8971819 | 0.90 | RARB (0.37) | PTPN11THRATHRBS1PR1FAAH | |
| SCHEMBL8971278 | 0.85 | PTPN11 (0.38) | PTPN11THRATHRBS1PR5S1PR1 | |
| SCHEMBL8971257 | 0.84 | FPR2 (0.32) | PTPN11 | |
| SCHEMBL8970598 | 0.83 | ALDH1A1 (0.34) | PTPN11S1PR5S1PR1 | |
| SCHEMBL8970621 | 0.83 | ALDH1A1 (0.34) | PTPN11S1PR5S1PR1 | |
| SCHEMBL8971756 | 0.82 | PTPN11 (0.36) | PTPN11THRATHRBS1PR5S1PR1 | |
| SCHEMBL8971747 | 0.82 | PTPN11 (0.36) | PTPN11THRATHRBS1PR5S1PR1 | |
| SCHEMBL8957200 | 0.82 | FPR2 (0.37) | PTPN11S1PR5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |