Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 9/20 | 0.36 |
| ▸ | CTSS | P25774 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031112 | 1.00 | NAALAD2 (0.65) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL1198859 | 0.86 | NAALAD2 (0.47) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL2566720 | 0.86 | NAALAD2 (0.47) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL28065098 | 0.84 | TDP1 (0.43) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL28168389 | 0.84 | NAALAD2 (0.43) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL7276633 | 0.83 | NAALAD2 (0.45) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL8627281 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL15619294 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1KMT2AGAACTSK | |
| Hydrochloric Acid SCHEMBL1740503 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1KMT2AGAACTSK | |
| SCHEMBL15619190 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1KMT2AGAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552427-A | ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0656210-A1 | Imidazole derivatives as glutaminose inhibitors | Takeda Chemical Industries, Ltd. (JP) | 1995-06-07 | — | — | EP | disclosed |