Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 8/20 | 0.36 |
| ▸ | CTSK | P43235 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909422 | 0.90 | NAALAD2 (0.40) | NAALAD2MEN1GAAKMT2AAKT1 | |
| SCHEMBL13623325 | 0.86 | DGAT1 (0.42) | MEN1GAAKMT2AAKT1CTSK | |
| SCHEMBL4907414 | 0.85 | MEN1 (0.39) | NAALAD2MEN1GAAKMT2AAKT1 | |
| SCHEMBL28065098 | 0.84 | TDP1 (0.43) | NAALAD2MEN1GAAKMT2ACTSS | |
| SCHEMBL28168389 | 0.84 | NAALAD2 (0.43) | NAALAD2MEN1GAAKMT2ACTSS | |
| SCHEMBL15619294 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1GAAKMT2AAKT1 | |
| SCHEMBL15619190 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1GAAKMT2ACTSS | |
| Hydrochloric Acid SCHEMBL1740503 | 0.82 | NAALAD2 (0.42) | NAALAD2MEN1GAAKMT2ACTSS | |
| SCHEMBL8971824 | 0.82 | NAALAD2 (0.65) | NAALAD2MEN1GAAKMT2ACTSS | |
| SCHEMBL3031112 | 0.82 | NAALAD2 (0.65) | NAALAD2MEN1GAAKMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |
| CN-1401621-A | Intermediate for preparing tricyclic compound and preparation method of intermediate | HOECHST MARION ROUSSEL INC (FR) | 2003-03-12 | — | — | CN | disclosed |
| US-5705333-A | Peptide-based nucleic acid mimics(PENAMS) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1996004000-A1 | PEPTIDE-BASED NUCLEIC ACID MIMICS (PENAMs) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-02-15 | — | — | WO | disclosed |