Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841182 | 0.87 | ATM (0.56) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL8972716 | 0.87 | ATM (0.56) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL2902518 | 0.85 | ATM (0.53) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL8971843 | 0.85 | ATM (0.53) | ELANEATMPRTN3CTSSCTSL | |
| SCHEMBL5194569 | 0.84 | ATM (0.58) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL4184372 | 0.84 | ATM (0.58) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL265847 | 0.84 | ATM (0.58) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL8971806 | 0.84 | ACACB (0.46) | NPC1RAB9A | |
| SCHEMBL12203687 | 0.83 | SYK (0.58) | ELANEATMCTSSCTSLCASP1 | |
| SCHEMBL8972112 | 0.83 | SYK (0.58) | ELANEATMCTSSCTSLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518903-A | HYDROLYSIS OF ESTER | CHISSO CORPORATION (JP) | 1996-05-21 | — | — | US | disclosed |