Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972067 | 0.86 | MTNR1A (0.62) | ACACBMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL8972162 | 0.85 | CTSK (0.45) | — | |
| SCHEMBL8978175 | 0.84 | MTNR1A (0.45) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL8971830 | 0.84 | ELANE (0.55) | NPC1RAB9A | |
| SCHEMBL8971765 | 0.83 | ALDH1A1 (0.54) | ACACBMTNR1AMTNR1BALDH1A1NPC1 | |
| SCHEMBL27470015 | 0.79 | ALDH1A1 (0.43) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL666155 | 0.78 | POLB (0.47) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL28454790 | 0.77 | ELANE (0.44) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL1870721 | 0.76 | LMNA (0.50) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL11060563 | 0.76 | CYP1A2 (0.58) | MTNR1AMTNR1BALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518903-A | HYDROLYSIS OF ESTER | CHISSO CORPORATION (JP) | 1996-05-21 | — | — | US | disclosed |