SCHEMBL8971866

SCHEMBL8971866

C[Si](Cl)(C1=CC=CC1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970964 0.82
SCHEMBL8196828 0.81
SCHEMBL7049972 0.80 ESR1 (0.33) ESR1ESR2
SCHEMBL7055264 0.80 ESR1 (0.42) ESR1ESR2
SCHEMBL4652615 0.80 ESR1 (0.33) ESR1ESR2
SCHEMBL9145200 0.78 ESR1 (0.32) ESR1ESR2
SCHEMBL9143179 0.78 ESR1 (0.32) ESR1ESR2
SCHEMBL4651356 0.78 ESR1 (0.30) ESR1ESR2
SCHEMBL7055426 0.78 ESR1 (0.30) ESR1ESR2
SCHEMBL7056345 0.78 ESR1 (0.30) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492974-A Process for preparing polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492973-A Polymer bound ligands PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492978-A Process for preparing catalyst system PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492985-A Polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492975-A Polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
EP-0690076-A1 Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-01-03 EP disclosed
US-5473020-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-12-05 US disclosed