Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 9/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971616 | 0.91 | HTR4 (0.54) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| SCHEMBL8971037 | 0.90 | HTR4 (0.56) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| SCHEMBL8971888 | 0.90 | HTR4 (0.56) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| SCHEMBL8971586 | 0.88 | MEN1 (0.52) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8972032 | 0.87 | MEN1 (0.51) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8971810 | 0.86 | MEN1 (0.51) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8971347 | 0.86 | HTR4 (0.53) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8972065 | 0.86 | MEN1 (0.50) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| SCHEMBL8971284 | 0.85 | MEN1 (0.57) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8970720 | 0.84 | MEN1 (0.50) | MEN1ALDH1A1CYP2D6KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |