SCHEMBL8972051

SCHEMBL8972051

CCCCCCCCOC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
NPC1 O15118 1/20 0.68
MAPT P10636 1/20 0.68
RAB9A P51151 1/20 0.68
CNR2 P34972 1/20 0.66
LMNA P02545 5/20 0.64
TSHR P16473 4/20 0.64
TDP1 Q9NUW8 1/20 0.64
MAPK1 P28482 2/20 0.61
CYP3A4 P08684 2/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
ESR1 P03372 1/20 0.59
CYP2D6 P10635 1/20 0.59
NR1H2 P55055 1/20 0.59
RNASEL Q05823 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
STS P08842 5/20 0.58
CYP2C9 P11712 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17737171 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL17737169 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL17685356 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL17737143 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL5710095 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL17737138 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL17737170 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL15907627 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL15907633 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2
SCHEMBL11757145 1.00 ALDH1A1 (0.68) ALDH1A1NPC1MAPTRAB9ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed
CN-1035107-A FLUORINATED OLIGOPHENYL DERIVATIVES MERCK PATENT GMBH (DE) 1989-08-30 CN disclosed
CN-85109049-A Ferroelectric liquid crystal material and electric-optical appliance thereof 1986-12-03 CN disclosed
CN-86101036-A Contain the liquid crystal material of terpenoid compound derivatives and the device of this material 1986-12-03 CN disclosed