Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451061 | 0.92 | TAAR1 (0.54) | IGF1RALOX15TAAR1HDAC3HDAC4 | |
| SCHEMBL9135033 | 0.89 | MAOB (0.44) | IGF1RALOX15HDAC3HDAC4HDAC1 | |
| SCHEMBL10365734 | 0.89 | IGF1R (0.64) | IGF1RALOX15TAAR1HDAC3HDAC4 | |
| SCHEMBL28966782 | 0.87 | IGF1R (0.61) | IGF1RALOX15TAAR1HDAC3HDAC4 | |
| SCHEMBL19223191 | 0.87 | ESR1 (0.44) | IGF1RALOX15MAOB | |
| SCHEMBL23837667 | 0.87 | ESR1 (0.44) | IGF1RALOX15MAOB | |
| SCHEMBL1115439 | 0.87 | IGF1R (0.61) | IGF1RALOX15TAAR1HDAC3HDAC4 | |
| SCHEMBL18440450 | 0.87 | ESR1 (0.44) | IGF1RALOX15MAOB | |
| SCHEMBL18050371 | 0.84 | TAAR1 (0.62) | IGF1RALOX15TAAR1HDAC3HDAC4 | |
| SCHEMBL9148266 | 0.83 | HDAC1 (0.50) | IGF1RALOX15HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545409-B1 | Liquid crystals with end groups containing more than one silane group | CONSORTIUM ELEKTROCHEM IND (DE) | 1996-03-06 | — | — | EP | disclosed |
| US-5399290-A | Liquid crystals with (polysila) alkyl wing groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0545409-A1 | Liquid crystals with end groups containing more than one silane group | Consortium für elektrochemische Industrie GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0131302-B1 | IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| EP-0122488-B1 | BIS-(PIPERAZINYL- OR HOMOPIPERAZINYL)-ALKANES | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1989-06-07 | — | — | EP | disclosed |
| US-4725597-A | ANTIALLERGEN, ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM LTD. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4581370-A | Antiarrhythmic imidazoliums | SCHERING A.G. (DE) | 1986-04-08 | — | — | US | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
| EP-0122488-A1 | Bis-(piperazinyl- or homopiperazinyl)-alkanes | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1984-10-24 | — | — | EP | disclosed |