Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972146 | 1.00 | GCGR (0.32) | GCGRPDE5ARARBRARARARG | |
| SCHEMBL9312574 | 1.00 | GCGR (0.32) | GCGRPDE5ARARBRARARARG | |
| SCHEMBL9312572 | 1.00 | GCGR (0.32) | GCGRPDE5ARARBRARARARG | |
| SCHEMBL9311991 | 0.92 | CYP11B1 (0.31) | — | |
| SCHEMBL8972392 | 0.92 | CYP11B1 (0.31) | — | |
| SCHEMBL8972400 | 0.92 | CYP11B1 (0.31) | — | |
| SCHEMBL9311996 | 0.92 | CYP11B1 (0.31) | — | |
| SCHEMBL9313050 | 0.87 | CYP11B1 (0.32) | — | |
| SCHEMBL8972651 | 0.87 | CYP11B1 (0.32) | — | |
| SCHEMBL9313045 | 0.87 | CYP11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433836-B1 | Halophenyl substituted dioxanes | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0433836-A2 | Halophenyl substituted dioxanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-26 | — | — | EP | disclosed |