Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313050 | 1.00 | CYP11B1 (0.32) | CYP11B1CYP11B2CYP17A1KDM1A | |
| SCHEMBL8972651 | 1.00 | CYP11B1 (0.32) | CYP11B1CYP11B2CYP17A1KDM1A | |
| SCHEMBL9311996 | 0.90 | CYP11B1 (0.31) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8972392 | 0.90 | CYP11B1 (0.31) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL9311991 | 0.90 | CYP11B1 (0.31) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8972400 | 0.90 | CYP11B1 (0.31) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8972155 | 0.87 | GCGR (0.32) | — | |
| SCHEMBL9312574 | 0.87 | GCGR (0.32) | — | |
| SCHEMBL9312572 | 0.87 | GCGR (0.32) | — | |
| SCHEMBL8972146 | 0.87 | GCGR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |