Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.34 |
| ▸ | PI4KA | P42356 | 5/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | GMPS | P49915 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063477 | 0.72 | ADORA1 (0.46) | ADORA1ADORA2AADORA3SLC28A1NT5E | |
| SCHEMBL7066965 | 0.71 | ADORA1 (0.43) | ADORA1ADORA2AADORA3NT5EAHCY | |
| SCHEMBL6879100 | 0.70 | ADORA1 (0.40) | ADORA1P2RY12NT5EAHCYEGFR | |
| SCHEMBL9218681 | 0.68 | ADORA1 (0.44) | ADORA1ADORA2AADORA3SLC28A1PI4KA | |
| SCHEMBL888265 | 0.68 | ADORA1 (0.35) | ADORA1ADORA2AADORA3NT5EPI4KA | |
| SCHEMBL8584884 | 0.66 | P2RY12 (0.48) | ADORA1P2RY12NT5EPI4KAPI4K2B | |
| SCHEMBL7621351 | 0.66 | P2RY12 (0.48) | ADORA1P2RY12NT5EPI4KAPI4K2B | |
| SCHEMBL8972151 | 0.66 | P2RY12 (0.48) | ADORA1P2RY12NT5EPI4KAPI4K2B | |
| SCHEMBL9548835 | 0.65 | ADORA2A (0.44) | ADORA1ADORA2AADORA3SLC28A1PI4KA | |
| SCHEMBL25390433 | 0.64 | ADORA1 (0.39) | ADORA1ADORA2AADORA3SLC28A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541307-A | Backbone modified oligonucleotide analogs and solid phase synthesis thereof | ISIS PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |