Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 5/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.42 |
| ▸ | GMPS | P49915 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227355 | 0.88 | PI4KA (0.37) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL2293030 | 0.86 | RXFP1 (0.42) | — | |
| SCHEMBL28036597 | 0.84 | SLC28A1 (0.53) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9548623 | 0.81 | ADORA3 (0.40) | ADORA3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9548802 | 0.80 | ADORA2A (0.42) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9548690 | 0.79 | ADORA2A (0.42) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL25389129 | 0.79 | PI4KA (0.41) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9548638 | 0.78 | ADORA2A (0.39) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL2290374 | 0.78 | TRPM2 (0.56) | — | |
| SCHEMBL7893477 | 0.77 | ADORA3 (0.44) | ADORA2AADORA3SLC28A1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |